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Article

Cancer cachexia-induced muscle atrophy: evidence for alterations in microRNAs important for muscle size

24 Mar 2017

Abstract excerpt

Muscle atrophy is a hallmark of cancer cachexia resulting in impaired function and quality of life and cachexia is the immediate cause of death for 20-40% of cancer patients. Multiple microRNAs (miRNAs) have been identified as being involved in muscle development and atrophy; however, less is known specifically on miRNAs in cancer cachexia. The purpose of this investigation was to examine the miRNA profile of...

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PMID: 28341621
DOI: 10.1152/physiolgenomics.00006.2017

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