Article

A FANCC intronic variant of uncertain significance in a child with metastatic pancreatic adenocarcinoma

2024-01-10

Abstract excerpt

<h4>Background: </h4> Pancreatic ductal adenocarcinoma (PDAC) has been reported to have a germline genetic association in about 5.5% of isolated cases and 10–13% of familial or hereditary cohorts. Studies are linking new germline variants to PDAC annually, with numerous variants of uncertain significance (VUS) in candidate genes being reported. Case presentation: A 9-year-old boy presented with a 3-week history o...

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Literature Corpus work: fafe5ee7-4c04-5a1c-be47-69d314ff44a8
DOI: 10.21203/rs.3.rs-3838058/v1

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