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Article

Prospective study of germline genetic testing in incident cases of pancreatic adenocarcinoma.

Cancer - 1 Sept 2018

Brand Randall, Borazanci Erkut, Speare Virginia, Dudley Beth, Karloski Eve, Peters Mary Linton B, Stobie Lindsey, Bahary Nathan, Zeh Herbert, Zureikat Amer, Hogg Melissa, Lee Kenneth, Tsung Allan, Rhee John, Ohr James, Sun Weijing, Lee James, Moser A James, DeLeonardis Kim, Krejdovsky Jill, Dalton Emily, LaDuca Holly, Dolinsky Jill, Colvin Arlene, Lim Cynthia, Black Mary Helen, Tung Nadine

Abstract excerpt

BACKGROUND: The objective of this study was to investigate the prevalence of pathogenic germline variants (PGVs) in 32 cancer susceptibility genes in individuals with newly diagnosed pancreatic ductal adenocarcinoma (PDAC). A key secondary objective was to evaluate how often PGVs would have been undetected with existing genetic testing criteria. METHODS: From May 2016 through May 2017, this multicenter cohort...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 30067863
DOI: 10.1002/cncr.31628

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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