The role of family history in predicting germline pathogenic variant carriers who develop pancreatic cancer: Results of a multicenter collaboration.

doi:10.1002/cncr.35383

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The role of family history in predicting germline pathogenic variant carriers who develop pancreatic cancer: Results of a multicenter collaboration.

Cancer - 1 Oct 2024

Karloski Eve, Dudley Beth, Diergaarde Brenda, Blanco Amie, Everett Jessica N, Levinson Elana, Rangarajan Tara, Stanich Peter P, Childers Kimberly, Brown Sandra, Drogan Christine, Cavestro Giulia Martina, Gordon Kelly, Singh Aparajita, Simeone Diane M, Reich Hannah, Kastrinos Fay, Zakalik Dana, Hampel Heather, Pearlman Rachel, Gordon Ora K, Kupfer Sonia S, Puzzono Marta, Zuppardo Raffaella Alessia, Brand Randall E

Abstract excerpt

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) surveillance is recommended for some individuals with a pathogenic or likely pathogenic variant (PV/LPV) in a PDAC susceptibility gene; the recommendation is often dependent on family history of PDAC. This study aimed to describe PDAC family history in individuals with PDAC who underwent genetic testing to determine the appropriateness of including a family...

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PMID: 38809542
DOI: 10.1002/cncr.35383
PMCID: PMC11371512

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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