Article

Array-based sequencing of filaggrin gene for comprehensive detection of disease-associated variants

2017-01-26

Abstract excerpt

<h4>ABSTRACT</h4> The filaggrin gene ( FLG ) is essential for skin differentiation and epidermal barrier formation with links to skin diseases, however it has a highly repetitive nucleotide sequence containing very limited stretches of unique nucleotides for precise mapping to reference genomes. Sequencing strategies using polymerase chain reaction (PCR) and conventional Sanger sequencing have been successful fo...

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Literature Corpus work: fab68d90-4b0f-546c-b497-5a5666aa769b
DOI: 10.1101/103416

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