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Article

A novel multiplex analysis of filaggrin polymorphisms: a universally applicable method for genotyping.

Clinica chimica acta; international journal of clinical chemistry - 9 Oct 2012

Meldgaard Michael, Szecsi Pal B, Carlsen Berit C, Thyssen Jacob P, Johansen Jeanne D, Menné Torkil, Stender Steen

Abstract excerpt

BACKGROUND: The filaggrin protein is expressed as profilaggrin mainly in stratum granulosum cells of the epidermis. The profilaggrin gene codes for 10-12 filaggrin repeats. The filaggrin protein is important for skin barrier function. Filaggrin deficiency due to functional null-polymorphisms affects 8-10% of the people in Northern Europe and is a strong risk factor for several diseases. Here, we describe a novel...

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Identifiers

PMID: 22705401
DOI: 10.1016/j.cca.2012.06.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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