Article

FERMI: A novel method for sensitive detection of rare mutations in somatic tissue

2017-10-25

Abstract excerpt

With growing interest in monitoring mutational processes in normal tissues, tumor heterogeneity, and cancer evolution under therapy, the ability to accurately and economically detect ultra-rare mutations is becoming increasingly important. However, this capability has often been compromised by significant sequencing, PCR and DNA preparation error rates. Here, we describe FERMI (Fast Extremely Rare Mutation Identif...

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Literature Corpus work: faaeabc3-3cbc-5517-9ab7-b95cf1d528e9
DOI: 10.1101/208066

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