Article

Oxysterol-liver X receptor signaling mediates CYFIP1 regulation of cortical neurogenesis

2023-06-26

Abstract excerpt

Dysregulation in neural progenitor proliferation and neuronal differentiation has been increasingly recognised as a common pathology in neural cells harboring genetic risks to neuropsychiatric and neurodevelopmental disorders, yet the underlying molecular mechanisms remains largely unknown. Deletions and duplications of the 15q11.2 region containing the CYFIP1 gene have been associated with autism and schizophreni...

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Literature Corpus work: faaa6402-279b-5fe7-82b9-ffd4c32b2365
DOI: 10.1101/2023.06.23.546272

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