Article
Emergence and genetic variation of neuraminidase stalk deletions in avian influenza viruses.
PloS one - 23 Feb 2011
Li Jinling, Zu Dohna Heinrich, Cardona Carol J, Miller Joy, Carpenter Tim E
Abstract excerpt
When avian influenza viruses (AIVs) are transmitted from their reservoir hosts (wild waterfowl and shorebirds) to domestic bird species, they undergo genetic changes that have been linked to higher virulence and broader host range. Common genetic AIV modifications in viral proteins of poultry isolates are deletions in the stalk region of the neuraminidase (NA) and additions of glycosylation sites on the...
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