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Article

H5N1 2.3.4.4b: a review of mammalian adaptations and risk of pandemic emergence.

The Journal of general virology - 1 Jun 2025

Capelastegui Fernando, Goldhill Daniel H

Abstract excerpt

Avian influenza viruses can cause severe disease when they spill over into mammalian and human hosts. H5N1 clade 2.3.4.4b has spread globally since 2021, decimating avian species, and has spilled over into mammalian species, causing sporadic infections and fatal outbreaks in sea lions, cats, mink and dairy cattle. Increased human cases of H5N1 are fuelling concern that H5N1 could soon adapt to become a new...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40465371
DOI: 10.1099/jgv.0.002109
PMCID: PMC12137919

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