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The hemagglutinin proteins of clades 1 and 2.3.4.4b H5N1 highly pathogenic avian influenza viruses exhibit comparable attachment patterns to avian and mammalian tissues

2025-06-04

Abstract excerpt

<h4>ABSTRACT</h4> The global spread of the A/goose/Guangdong/1/96-lineage H5N1 highly pathogenic avian influenza (HPAI) viruses is accompanied by an expanded host range and the establishment of sustained viral transmission among dairy cattle. To evaluate if the evolving H5N1 viruses have changed tissue tropism over time, we compared the binding patterns of recombinant hemagglutinin (HA) proteins derived from clad...

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Identifiers and source

Literature Corpus work
0657557c-926e-58c9-bf76-4fd78d5c08ab
DOI
10.1101/2025.06.02.657404
Open publication

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The hemagglutinin proteins of clades 1 and 2.3.4.4b H5N1 highly pathogenic avian influenza viruses exhibit comparable attachment patterns to avian and mammalian tissuesDOI 10.1101/2025.06.02.657404
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