Article
Neuraminidase antigenic drift of Influenza A virus H3N2 clade 3c.2a viruses alters virus replication, enzymatic activity and inhibitory antibody binding
2020-02-20
Abstract excerpt
In the 2014-2015 influenza season a novel neuraminidase (NA) genotype emerged in the Johns Hopkins Center of Excellence for Influenza Research and Surveillance (JH CEIRS) surveillance network as well as globally. This novel genotype encoded a glycosylation site at position 245-247 in the NA protein from clade 3c.2a H3N2 viruses. In the years following the 2014-2015 season, this novel NA glycosylation genotype quic...
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Identifiers and source
- Literature Corpus work
- f97167dd-7946-57ed-8432-c85c0dedf1e7
- DOI
- 10.1101/2020.02.20.957399
