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Article

Reversible Transcriptomic Age Shifts from Physiological Stress in Whole Blood

2024-09-09

Abstract excerpt

We developed a genome-wide transcriptomic clock for predicting chronological age using whole blood samples from 463 healthy individuals. Our findings reveal profound age acceleration, up to 24.47 years, under perturbed homeostasis in COVID-19 patients, which reverted to baseline upon recovery. This study demonstrates that the whole blood transcriptome can track reversible changes in biological age induced by stres...

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Identifiers and source

Literature Corpus work
ab0622cf-bd3a-5568-a921-f8de52e80c90
DOI
10.1101/2024.09.08.611853
Open publication

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Reversible Transcriptomic Age Shifts from Physiological Stress in Whole BloodDOI 10.1101/2024.09.08.611853
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