Article

Antibodies control metabolism by regulating insulin homeostasis

2021-08-10

Abstract excerpt

<h4>Summary</h4> Homeostasis of metabolism by hormone production is crucial to maintain physiological integrity and disbalance can cause severe metabolic disorders such as diabetes mellitus. Here, we show that antibodies recognizing insulin are key regulators of blood glucose and metabolism controlling insulin concentrations. In fact, antibody-deficient mice and immunodeficiency patients show sub-physiological bl...

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Literature Corpus work: f9af7603-048e-5619-8a02-f88305c39b2f
DOI: 10.1101/2021.08.10.455644

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