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Article

Beyond the hormone: insulin as an autoimmune target in type 1 diabetes.

Endocrine reviews - 1 Oct 2011

Brezar Vedran, Carel Jean-Claude, Boitard Christian, Mallone Roberto

Abstract excerpt

Insulin is not only the hormone produced by pancreatic β-cells but also a key target antigen of the autoimmune islet destruction leading to type 1 diabetes. Despite cultural biases between the fields of endocrinology and immunology, these two facets should not be regarded separately, but rather harmonized in a unifying picture of diabetes pathogenesis. There is increasing evidence suggesting that metabolic...

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PMID: 21700723
DOI: 10.1210/er.2011-0010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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