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Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease

15 May 2020

Abstract excerpt

Cell replacement is a long-standing and realistic goal for the treatment of Parkinson's disease (PD). Cells for transplantation can be obtained from fetal brain tissue or from stem cells. However, after transplantation, dopamine (DA) neurons are seen to be a minor component of grafts, and it has remained difficult to determine the identity of other cell types. Here, we report analysis by single-cell RNA...

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PMID: 32415072
DOI: 10.1038/s41467-020-16225-5

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