Article

Red blood cell tension controls <i>Plasmodium falciparum</i> invasion and protects against severe malaria in the Dantu blood group

2018-11-21

Abstract excerpt

Malaria has had a major effect on the human genome, with many protective polymorphisms such as sickle cell trait having been selected to high frequencies in malaria endemic regions 1, 2 . Recently, we showed that a novel blood group variant, Dantu, provides 74% protection against all forms of severe malaria in homozygous individuals 3-5 . This is a similar degree of protection to sickle cell trait and considerab...

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Literature Corpus work: f973d67e-459c-5417-916e-cc44051d5ca8
DOI: 10.1101/475442

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