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The erythrocyte membrane properties of beta thalassaemia heterozygotes and their consequences for <i>Plasmodium falciparum</i> invasion

2022-01-14

Abstract excerpt

Malaria parasites such as Plasmodium falciparum have exerted formidable selective pressures on the human genome. Of the human genetic variants associated with malaria protection, beta thalassaemia (a haemoglobinopathy) was the earliest to be associated with malaria prevalence. However, the malaria protective properties of beta thalassaemic erythrocytes remain unclear. Here we studied the mechanics and surface pro...

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Identifiers and source

Literature Corpus work
81dbe8cf-0afa-5147-87c3-17590c2a822c
DOI
10.1101/2022.01.13.476158
Open publication

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The erythrocyte membrane properties of beta thalassaemia heterozygotes and their consequences for <i>Plasmodium falciparum</i> invasionDOI 10.1101/2022.01.13.476158
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