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Invasion preferences suggest a possible role for <i>Plasmodium falciparum</i> parasites in the expansion of Duffy negativity in West and Central Africa

2025-07-11

Abstract excerpt

<h4>ABSTRACT</h4> Duffy antigen receptor for chemokines (DARC) is the primary red blood cell (RBC) receptor for invasion of human RBCs by Plasmodium vivax and knowlesi parasites. By contrast, Plasmodium falciparum parasites use multiple RBC receptors for invasion. Whether DARC is one of these receptors has never been systematically explored. We used flow cytometry and microscopy-based approaches to investigate...

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Literature Corpus work
2eddd590-dd67-576f-a779-d7d317780558
DOI
10.1101/2025.07.09.663497
Open publication

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Invasion preferences suggest a possible role for <i>Plasmodium falciparum</i> parasites in the expansion of Duffy negativity in West and Central AfricaDOI 10.1101/2025.07.09.663497
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