Article

Antigen presentation requirements for effective cDC1-based cancer immunotherapy

2026-01-26

Abstract excerpt

Type 1 conventional dendritic cells (cDC1s) are important for generating and sustaining antitumor immunity. Accordingly, the abundance of cDC1s in human tumors correlates with improved outcomes in cancer. Capitalizing on this role, we previously demonstrated that vaccination with in vitro -derived murine cDC1s elicits durable tumor control in multiple preclinical models; however, the immunological mechanisms unde...

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Literature Corpus work: f96ae616-07bf-5512-b134-8ce2dac84900
DOI: 10.64898/2026.01.24.701412

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