Refining Dendritic Cell-Based Cancer Vaccines: Subset Targeting, Translational Barriers, and Emerging Strategies

Abstract excerpt

Dendritic cells function as professional antigen-presenting cells and serve as essential coordinators between the innate and adaptive immune systems.This immunological role of DCs was first identified by Steinman and Cohn in 1973 [1].DCs reside in peripheral and lymphoid tissues and are equipped to internalize antigens, undergo maturation, and activate naive T cells.DCs can precisely recognize exogenous antigens...