Article
Dendritic cell vaccines in melanoma: from promise to proof?
Critical reviews in oncology/hematology - 1 May 2008
Lesterhuis W J, Aarntzen E H J G, De Vries I J M, Schuurhuis D H, Figdor C G, Adema G J, Punt C J A
Abstract excerpt
Dendritic cells (DC) are the directors of the immune system, capable of inducing tumour antigen-specific T- and B-cell responses. As such, they are currently applied in clinical studies in cancer patients. Early small clinical trials showed promising results, with frequent induction of anti-cancer immune reactivity and clinical responses. In recent years, additional trials have been carried out in melanoma...
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