Article

Identification of disease-specific TCRs maintaining pathogenic T helper cell responses in postinfectious Lyme Arthritis

2024-01-20

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Antibiotic-Refractory Lyme Arthritis(ARLA) involves a complex interplay of T cell responses targeting Borrelia burgdorferi antigens succeeding towards autoantigens by epitope spreading. However, the precise molecular mechanisms driving the pathogenic T cell response in ARLA remain unclear. Our aim was to elucidate the molecular program of disease-specific Th cells. <h4>Methods...

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Literature Corpus work: f959d7b0-9b26-5afa-8238-b4b31478edc3
DOI: 10.1101/2024.01.18.24301314

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