Article

Generation of a T cell receptor, cytokine and cell repertoire synovial fluid atlas to define commonalities and dissimilarities between arthritic diseases through systems immunology approaches

2025-01-14

Abstract excerpt

<h4>ABSTRACT</h4> Although different chronic arthritic diseases are defined by clinical factors like gender, psoriasis and auto-antibodies, the biology of inflamed joints while comparing the different diseases remains neglected. Here, after curating an inflamed joint derived T-cell receptor (TCR) database, our new TRIASSIC tool identified 66303 significantly convergent TCR clonotypes. Clustering TCR clonotypes sh...

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Literature Corpus work: e4b1033e-9456-5639-8464-318465e67109
DOI: 10.1101/2025.01.10.632345

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