Article

Panomics reveals patient-individuality as the major driver for colorectal cancer progression

2022-10-07

Abstract excerpt

Colorectal cancer (CRC) is one of the most prevalent cancers, with over one million new cases. The prognosis of CRC considerably depends on the disease stage and metastatic status. As precision oncology for patients with CRC continues to improve, this study aims to integrate genomic, transcriptomic, and proteomic analyses to identify significant expression differences during colorectal progression using a unique s...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f92c1946-9596-52cf-8c60-db18d2f6d26c
DOI: 10.1101/2022.10.06.22280355

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Panomics reveals patient-individuality as the major driver for colorectal cancer progressionDOI 10.1101/2022.10.06.22280355Read

A Portrait of Intratumoral Genomic and Transcriptomic Heterogeneity at Single-Cell Level in Colorectal CancerSemantic proximity Read

High-Resolution Spatial Proteomics Characterises Colorectal Cancer Consensus Molecular SubtypesSemantic proximity Read

Bulk and Single-Cell Next-Generation Sequencing: Individualizing Treatment for Colorectal CancerSemantic proximity Read

Proof-of-concept pilot study on comprehensive spatiotemporal intra-patient heterogeneity for colorectal cancer with liver metastasisSemantic proximity Read

Spatial and single‐cell transcriptomic analysis reveals fibroblasts dependent immune environment in colorectal cancerSemantic proximity Read

Proteome Heterogeneity in Colorectal Cancer.Semantic proximity Read

Intratumor CMS Heterogeneity Impacts Patient Prognosis in Localized Colon CancerSemantic proximity Read

Integrated multi-omics analyses on patient-derived CRC organoids highlight altered molecular pathways in colorectal cancer progression involving PTENSemantic proximity Read

Proteomic Landscape of Colorectal Cancer Derived Liver Metastasis Reveals Three Distinct Phenotypes With Specific Signaling and Enhanced SurvivalSemantic proximity Read

An epithelial cell fate-driven predictive model for liver metastasis risk in primary colorectal cancer through single-cell and multi-omics integration.Semantic proximity Read

How Can We Improve Subtyping of Colon Adenocarcinoma for Precision Oncology? Multi-Omics Consensus Clustering Reveals Immunologically Active and Therapeutically Distinct Molecular Groups.Semantic proximity Read

Heterogeneity in Colorectal Cancer: A Challenge for Personalized Medicine?Semantic proximity Read