Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Intratumor CMS Heterogeneity Impacts Patient Prognosis in Localized Colon Cancer

24 Jun 2021

Abstract excerpt

PURPOSE: The consensus molecular subtypes (CMS) represent a significant advance in the understanding of intertumor heterogeneity in colon cancer. Intratumor heterogeneity (ITH) is the new frontier for refining prognostication and understanding treatment resistance. This study aims at deciphering the transcriptomic ITH of colon cancer and understanding its potential prognostic implications. EXPERIMENTAL DESIGN: We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to Ferroptosis and cancer prognosis
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34168047
DOI: 10.1158/1078-0432.ccr-21-0529

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Intratumor CMS Heterogeneity Impacts Patient Prognosis in Localized Colon CancerPMID 34168047Read ↗

Exploring and modelling colon cancer inter-tumour heterogeneity: opportunities and challengesSemantic proximity Read ↗

Multiregional transcriptomics identifies congruent consensus molecular subtypes with prognostic value beyond tumor heterogeneity in colorectal cancer.Semantic proximity Read ↗

Multiregional transcriptomics identifies congruent consensus subtypes with prognostic value beyond tumor heterogeneity of colorectal cancerSemantic proximity Read ↗

The consensus molecular subtypes of colorectal cancer.Semantic proximity Read ↗

High-Resolution Spatial Proteomics Characterises Colorectal Cancer Consensus Molecular SubtypesSemantic proximity Read ↗

Refining colorectal cancer classification and clinical stratification through a single-cell atlasSemantic proximity Read ↗

CMScaller: an R package for consensus molecular subtyping of colorectal cancer pre-clinical modelsSemantic proximity Read ↗

A Clinically Applicable Gene-Expression Classifier Reveals Intrinsic and Extrinsic Contributions to Consensus Molecular Subtypes in Primary and Metastatic Colon CancerSemantic proximity Read ↗

Characterizing heterogeneity along EMT and metabolic axes in colorectal cancer reveals underlying consensus molecular subtype-specific trendsSemantic proximity Read ↗

Context matters-consensus molecular subtypes of colorectal cancer as biomarkers for clinical trials.Semantic proximity Read ↗

Colorectal premalignancy is associated with consensus molecular subtypes 1 and 2Semantic proximity Read ↗

Redefining colorectal cancer classification and clinical stratification through a single-cell atlasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.