Article

<i>Mecp2</i> knock-out astrocytes affect synaptogenesis by IL-6 dependent mechanisms

2023-02-08

Abstract excerpt

Synaptic abnormalities represent a hallmark for several neurological diseases and clarification of the underlying mechanisms constitutes a crucial step towards the development of therapeutic strategies. Rett syndrome (RTT) is a rare neurodevelopmental disorder, mainly affecting females, caused by heterozygous mutations in the X-linked Methyl-CpG-Binding Protein 2 ( MECP2 ) gene, leading to a deep derangement of s...

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Literature Corpus work: f92742d4-0656-5906-80d0-4141f76f59ee
DOI: 10.1101/2023.02.08.527630

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