Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Down Syndrome iPSC-Derived Astrocytes Impair Neuronal Synaptogenesis and the mTOR Pathway In Vitro

11 Nov 2017

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Congenital heart defects research
Share to Down syndrome and intellectual disability research
Share to Genetics and Neurodevelopmental Disorders

Source

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 29128905
DOI: 10.1007/s12035-017-0818-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 19 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Down Syndrome iPSC-Derived Astrocytes Impair Neuronal Synaptogenesis and the mTOR Pathway In VitroPMID 29128905Read ↗

Astrocytes in Down Syndrome Across the LifespanSemantic proximity Read ↗

Generation of functional iPSC-derived astrocytes to model the neurodevelopmental disorder, Rett SyndromeSemantic proximity Read ↗

mTOR signaling in neural stem cells: from basic biology to diseaseSemantic proximity Read ↗

Potential Role of JAK-STAT Signaling Pathway in the Neurogenic-to-Gliogenic Shift in Down Syndrome BrainSemantic proximity Read ↗

An Efficient Direct Conversion Strategy to Generate Functional Astrocytes from Human Adult FibroblastsSemantic proximity Read ↗

Zika Virus NS4A and NS4B Proteins Deregulate Akt-mTOR Signaling in Human Fetal Neural Stem Cells to Inhibit Neurogenesis and Induce AutophagySemantic proximity Read ↗

Neuron-Glia Interactions Increase Neuronal Phenotypes in Tuberous Sclerosis Complex Patient iPSC-Derived ModelsSemantic proximity Read ↗

Compromised lipid metabolism, mitochondria respiration and neuroprotective effects in iPSC-derived astrocytes from a Smith-Lemli-Opitz syndrome patient.Semantic proximity Read ↗

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells (NPCs).Semantic proximity Read ↗

Abnormal neuronal and synaptic morphology in Down syndrome brains reproduces in human isogenic cellular modelsSemantic proximity Read ↗

Human and mouse iPSC-derived astrocyte subtypes reveal vulnerability in Vanishing White MatterSemantic proximity Read ↗

GABA/Glutamate neuron differentiation imbalance and increased AKT/mTOR signalling in CNTNAP2 <sup>-/-</sup> cerebral organoidsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.