Article

Small leucine zipper protein regulates glucose metabolism of prostate cancer cells via induction of phosphoglycerate kinase 1

2024-09-09

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Cancer cells exhibit an altered metabolism, whereby glucose is preferentially utilized to produce lactate through aerobic glycolysis. Increased lactate production creates an acidic microenvironment that supports tumor progression and metastasis. Human small leucine zipper protein (sLZIP) is involved in the transcriptional regulation of genes related to the migrat...

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Literature Corpus work: 9025afc3-8d3c-5630-aea2-0ee84aac1af8
DOI: 10.21203/rs.3.rs-4898593/v1

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