Article

RNF185 control of COL3A1 expression limits prostate cancer migration and metastatic potential

2023-07-01

Abstract excerpt

RNF185 is a RING finger domain-containing ubiquitin ligase implicated in ER-associated degradation. Prostate tumor patient data analysis revealed a negative correlation between RNF185 expression and prostate cancer progression and metastasis. Likewise, several prostate cancer cell lines exhibited greater migration and invasion capabilities in culture upon RNF185 depletion. Subcutaneous inoculation of mouse prostat...

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Identifiers and source

Literature Corpus work: 10543238-4b1b-53b3-818e-e22cb672c7b6
DOI: 10.1101/2023.06.29.547118

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