Article
Targeting Key Players of Neuroendocrine Differentiation in Prostate Cancer.
International journal of molecular sciences - 5 Sept 2023
Zamora Irene, Freeman Michael R, Encío Ignacio J, Rotinen Mirja
Abstract excerpt
Neuroendocrine prostate cancer (NEPC) is a highly aggressive subtype of prostate cancer (PC) that commonly emerges through a transdifferentiation process from prostate adenocarcinoma and evades conventional therapies. Extensive molecular research has revealed factors that drive lineage plasticity, uncovering novel therapeutic targets to be explored. A diverse array of targeting agents is currently under...
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