Article

Exploring Genetic Interactions with Rare Variants Reveals Gene Networks Susceptible to Complex Diseases

2024-12-17

Abstract excerpt

Genetic interactions play a crucial role in understanding the susceptibility and etiology of complex human diseases. However, existing methods for analyzing gene-gene interactions are often limited to common variants and may not capture the effects of rare variants. In this study, we propose a novel method called GGI-RUNNER that is specifically designed for analyzing gene-gene interactions of rare variants. GGI-RU...

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Literature Corpus work: f86de4ce-bfbf-57d7-91c9-c0501e8bd15a
DOI: 10.1101/2024.12.17.628845

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