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Article

GxGrare: gene-gene interaction analysis method for rare variants from high-throughput sequencing data.

BMC systems biology - 19 Mar 2018

Kwon Minseok, Leem Sangseob, Yoon Joon, Park Taesung

Abstract excerpt

BACKGROUND: With the rapid advancement of array-based genotyping techniques, genome-wide association studies (GWAS) have successfully identified common genetic variants associated with common complex diseases. However, it has been shown that only a small proportion of the genetic etiology of complex diseases could be explained by the genetic factors identified from GWAS. This missing heritability could possibly...

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Identifiers

PMID: 29560826
DOI: 10.1186/s12918-018-0543-4
PMCID: PMC5861485

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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