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Article

A general framework for detecting disease associations with rare variants in sequencing studies.

American journal of human genetics - 9 Sept 2011

Lin Dan-Yu, Tang Zheng-Zheng

Abstract excerpt

Biological and empirical evidence suggests that rare variants account for a large proportion of the genetic contributions to complex human diseases. Recent technological advances in high-throughput sequencing platforms have made it possible for researchers to generate comprehensive information on rare variants in large samples. We provide a general framework for association testing with rare variants by combining...

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Identifiers

PMID: 21885029
DOI: 10.1016/j.ajhg.2011.07.015
PMCID: PMC3169821

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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