Article

The early macrophage response to pathogens requires dynamic regulation of the nuclear paraspeckle

2023-05-14

Abstract excerpt

<h4>ABSTRACT</h4> To ensure a robust immune response to pathogens without risking immunopathology, the kinetics and amplitude of inflammatory gene expression in macrophages needs to be exquisitely well-controlled. There is a growing appreciation for stress-responsive membraneless organelles (MLOs) regulating various steps of eukaryotic gene expression in response to extrinsic cues. Here, we implicate the nuclear...

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Literature Corpus work: f8489d51-65b4-5ff1-af59-61e69a67f7d0
DOI: 10.1101/2023.05.11.540384

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