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Article

Cytoplasmic RNA Granules and Viral Infection

1 Oct 2014

Abstract excerpt

RNA granules are dynamic cellular structures essential for proper gene expression and homeostasis. The two principal types of cytoplasmic RNA granules are stress granules, which contain stalled translation initiation complexes, and processing bodies (P bodies), which concentrate factors involved in mRNA degradation. RNA granules are associated with gene silencing of transcripts; thus, viruses repress RNA granule...

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PMID: 26958719
DOI: 10.1146/annurev-virology-031413-085505

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