Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

VraSR and Virulence Trait Modulation during Daptomycin Resistance in Methicillin-Resistant Staphylococcus aureus Infection

12 Feb 2019

Abstract excerpt

continues to develop resistance to antimicrobials, including those in current clinical use as daptomycin (DAP). Resistance to DAP arises by mutations in cell membrane and cell wall genes and/or upregulation of the two-component VraSR system. However, less is known about the connection between the pathogen and virulence traits during DAP resistance development. We provide new insights into VraSR and its regulatory...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial Resistance in Staphylococcus
Share to Bacterial biofilms and quorum sensing
Share to Plant Pathogenic Bacteria Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30760612
DOI: 10.1128/msphere.00557-18

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

VraSR and Virulence Trait Modulation during Daptomycin Resistance in Methicillin-Resistant Staphylococcus aureus InfectionPMID 30760612Read ↗

VraSR two-component regulatory system contributes to mprF-mediated decreased susceptibility to daptomycin in in vivo-selected clinical strains of methicillin-resistant Staphylococcus aureus.Semantic proximity Read ↗

A novel mutation in the vraS gene of Staphylococcus aureus contributes to reduce susceptibility against daptomycin.Semantic proximity Read ↗

Molecular Bases Determining Daptomycin Resistance-Mediated Resensitization to β-Lactams (Seesaw Effect) in Methicillin-Resistant Staphylococcus aureus.Semantic proximity Read ↗

Two-component signaling pathways modulate drug resistance ofSemantic proximity Read ↗

An induced mutation of ABC-transporter component VraF(K84E) contributes to vancomycin resistance and virulence in Staphylococcus aureus strain MW2.Semantic proximity Read ↗

Evolution of multidrug resistance during Staphylococcus aureus infection involves mutation of the essential two component regulator WalKR.Semantic proximity Read ↗

Down-regulation of the two-component system and cell-wall biosynthesis-related genes was associated with the reversion to daptomycin susceptibility in daptomycin non-susceptible methicillin-resistant Staphylococcus aureus.Semantic proximity Read ↗

Molecular Events for Promotion of Vancomycin Resistance in Vancomycin Intermediate Staphylococcus aureusSemantic proximity Read ↗

Identification and characterisation of a novel mechanism of antibiotic resistanceSemantic proximity Read ↗

VraH Is the Third Component of the Staphylococcus aureus VraDEH System Involved in Gallidermin and Daptomycin Resistance and PathogenicitySemantic proximity Read ↗

Antimicrobial resistance in methicillin-resistant staphylococcus aureusSemantic proximity Read ↗

Genetics of antibiotic resistance in methicillin-resistant Staphylococcus aureus (MRSA)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.