Article

Intratumoral Cellular Heterogeneity Critically Determines Extracellular Vesicle Uptake in Colorectal Cancer

2021-03-22

Abstract excerpt

<title>Abstract</title> <p>The majority of colorectal cancer (CRC) patients carry mutations in the <italic>APC</italic> gene, which leads to an unregulated activation of the Wnt pathway. Extracellular vesicles (EV) are considered as potential therapeutic tools. Although CRC is a genetically heterogenous disease, the significance of the inter- and intra-tumor heterogeneity in EV uptake of CRC cells is not yet know...

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Literature Corpus work: f8429829-a3ba-5533-b034-b3759126880e
DOI: 10.21203/rs.3.rs-300126/v1

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