Article

Age dependent trans-cellular propagation of human tau aggregates in <i>Drosophila</i> disease models

2020-03-29

Abstract excerpt

Tauopathies is a class of neurodegenerative disorders which involves the transformation of physiological tau into pathogenic tau. One of the prime causes reported to drive this conversion is tau hyperphosphorylation and the subsequent propagation of pathogenic protein aggregates across the nervous system. Although past attempts have been made to deduce the details of tau propagation, yet not much is known about it...

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Literature Corpus work: f83fa4f8-94d5-5150-9d71-51105a58f571
DOI: 10.1101/2020.03.28.013136

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