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Article

Drosophila Models of Tauopathies: What Have We Learned?

1 Jan 2012

Abstract excerpt

Aggregates of the microtubule-associated protein Tau are neuropathological hallmark lesions in Alzheimer's disease (AD) and related primary tauopathies. In addition, Tau is genetically implicated in a number of human neurodegenerative disorders including frontotemporal dementia (FTD) and Parkinson's disease (PD). The exact mechanism by which Tau exerts its neurotoxicity is incompletely understood. Here, we give...

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PMID: 22701808
DOI: 10.1155/2012/970980

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