Article
New Models for MPNST: Establishment and Comprehensive Characterization of Two Tumor Cell Lines
2025-04-30
Abstract excerpt
<title>Abstract</title> <p><bold>Background</bold> Malignant peripheral nerve sheath tumors (MPNSTs) are rare, invasive, and aggressive soft tissue sarcomas arising from peripheral nerves. They may occur sporadically or in association with Neurofibromatosis type 1 (NF1), in which they are the leading cause of mortality. Currently, there are no effective therapies other than surgery. Therefore, tumor-derived cell...
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Identifiers and source
- Literature Corpus work
- f830d25c-0df4-52ce-96b2-29930efbc1f5
- DOI
- 10.21203/rs.3.rs-6219394/v1
