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Identification of Malignant Peripheral Nerve Sheath Tumor subtypes with distinct genomic identities

2026-04-02

Abstract excerpt

<h4>ABSTRACT</h4> Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft-tissue sarcomas arising sporadically or in people with neurofibromatosis type 1 (NF1). Their marked heterogeneity challenges diagnosis and has hampered an integrative view of MPNST molecular pathogenesis. Here, a thorough whole-genome and transcriptome analysis of MPNSTs and the re-analysis of a large independent cohort allowe...

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Literature Corpus work
9801ee91-d47f-5e2d-a6ca-2a3d27dda19d
DOI
10.64898/2026.03.31.715523
Open publication

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Identification of Malignant Peripheral Nerve Sheath Tumor subtypes with distinct genomic identitiesDOI 10.64898/2026.03.31.715523
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