Article
Accelerating functional gene discovery in osteoarthritis
2019-11-10
Abstract excerpt
Osteoarthritis causes debilitating pain and disability, resulting in a huge socioeconomic burden, yet no drugs are available that prevent disease onset or progression. Here, we develop, validate and use rapid-throughput imaging techniques to identify abnormal joint phenotypes in unselected mutant mice generated by the International Knockout Mouse Consortium. We identify 14 genes with functional involvement in oste...
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Identifiers and source
- Literature Corpus work
- f82230bd-8052-5a4a-96ba-67bc2f691ff5
- DOI
- 10.1101/836221