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Integrins Alpha-2 and Beta-1 expression increases through Multiple Generations of the EDW01 Patient-Derived Xenograft Model of Breast Cancer - insight into their role in Epithelial Mesenchymal Transition in vivo gained from an in vitro model system

2020-09-03

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Breast cancers acquire aggressive capabilities via epithelial to mesenchymal transition (EMT), in which various integrins/integrin linked kinase signalling are upregulated. <bold>Methods:</bold> We investigated this in two patient-derived xenografts (PDXs) developed from breast-to-bone metastases, and it’s functional significance in a breast cancer cell line sys...

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Literature Corpus work: f80c7871-cb2a-5069-b5bf-ebe83ef05d72
DOI: 10.21203/rs.3.rs-16180/v3

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Integrins Alpha-2 and Beta-1 expression increases through Multiple Generations of the EDW01 Patient-Derived Xenograft Model of Breast Cancer - insight into their role in Epithelial Mesenchymal Transition in vivo gained from an in vitro model systemDOI 10.21203/rs.3.rs-16180/v3Read

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