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Article

Epithelial-Mesenchymal Transition—A Hallmark of Breast Cancer Metastasis

1 Mar 2013

Abstract excerpt

Epithelial-mesenchymal transition (EMT) is a highly conserved cellular program that converts polarized, immotile epithelial cells to migratory mesenchymal cells. In addition, EMT was initially recognized as a key step for morphogenesis during embryonic development. Emerging evidences indicate that this important developmental program promotes metastasis, drug resistance, and tumor recurrence, features that are...

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Identifiers

PMID: 24611128
DOI: 10.1166/ch.2013.1004

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