Article
An In Vitro Approach to Model EMT in Breast Cancer.
International journal of molecular sciences - 24 Apr 2023
Isert Lorenz, Mehta Aditi, Loiudice Gabriele, Oliva Altea, Roidl Andreas, Merkel Olivia M
Abstract excerpt
During the progression from ductal carcinoma in situ (DCIS) to invasive breast cancer (IBC), cells must overcome the physically restraining basement membrane (BM), which compartmentalizes the epithelium from the stroma. Since the extracellular matrix (ECM) of the epithelial and stromal compartments are biochemically and physically distinct from one another, the progression demands a certain degree of cellular...
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