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New generation breast cancer cell lines developed from patient-derived xenografts

23 Jun 2020

Abstract excerpt

BACKGROUND: Breast cancer is a highly heterogeneous disease characterized by multiple histologic and molecular subtypes. While a myriad of breast cancer cell lines have been developed over the past 60 years, estrogen receptor alpha (ER)+ disease and some mutations associated with this subtype remain underrepresented. Here we describe six breast cancer cell lines derived from patient-derived xenografts (PDX) and...

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PMID: 32576280
DOI: 10.1186/s13058-020-01300-y

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