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Article

Breast cancer cells interact with tumor-derived extracellular matrix in a molecular subtype-specific manner

18 Jan 2023

Abstract excerpt

Mimicking the native microenvironment is vital for tumor engineering. Breast cancer is a highly heterogeneous disease with various molecular subtypes exhibiting distinct biological behaviors and treatment responsiveness. The heterogeneity of extracellular matrix (ECM) of breast cancer has remained largely unexplored and underestimated. The present study addressed this issue by comparing the composition,...

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PMID: 36709629
DOI: 10.1016/j.bioadv.2023.213301

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