Article

Disease mutation study identifies essential residues for phosphatidylserine flippase ATP11A

2020-01-13

Abstract excerpt

PS flippase (P4-ATPase) transports PS from the outer to the inner leaflet of the lipid bilayer in the membrane to maintain PS asymmetry, which is important for biological activity of the cell. ATP11A is expressed in multiple tissues and plays a role in myotube formation. However, detailed cellular function of ATP11A remains elusive. Mutation analysis revealed that I91, L308 and E897 residues in ATP8A2 are importan...

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Literature Corpus work: f7de2207-bf8b-51b4-b0c0-5d49d04cc601
DOI: 10.1101/2020.01.13.904045

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