Towards defining the substrate of orphan P5A-ATPases.

Abstract excerpt

BACKGROUND: P-type ATPases are ubiquitous ion and lipid pumps found in cellular membranes. P5A-ATPases constitute a poorly characterized subfamily of P-type ATPases present in all eukaryotic organisms but for which a transported substrate remains to be identified. SCOPE OF REVIEW: This review aims to discuss the available evidence which could lead to identification of possible substrates of P5A-ATPases. MAJOR...

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